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POSTDOCTORAL POSITION FCT
PUBLIC NOTICE FOR AN INTERNATIONAL CALL FOR APPLICATIONS FOR THE POST OF POST-DOCTORAL RESEARCHER WITHIN THE FRAMEWORK OF THE PROJECT 2022.01782.PTDC Novel mitotic DNA topology regulators by Fundação para a Ciência e Tecnologia
PUBLIC NOTICE FOR AN INTERNATIONAL CALL FOR APPLICATIONS FOR THE POST OF POST-DOCTORAL RESEARCHER WITHIN THE FRAMEWORK OF THE PROJECT 2022.01782.PTDC Novel mitotic DNA topology regulators by Fundação para a Ciência e Tecnologia
Have you ever wondered... how is DNA disentangled during mitosis?
The double helical structure of DNA imposes a major challenge to all processes involving this molecule: access to its sequence. This requires DNA unwinding, which creates massive changes in the topology of DNA, inducing helical torsion, supercoiling and ultimately sister chromatid intertwining. These topological changes are problematic and need to be resolved to ensure genome stability. This proposal aims to uncover novel topology regulators that operate during mitosis, in order to achieve timely and efficient genome partition at every cell division.
Do you want to join the team?
Eligibility / Requirements: We are seeking a highly motivated and ambitious candidate with a PhD in biological sciences or related areas. Solid expertise in Drosophila genetics and development, chromosome biology and/or live imaging techniques, although not essential, will be considered an advantage. We expect the candidate to drive his/her project with a high degree of independence but within the open-minded collaborative atmosphere of the lab. Good communication skills, including a good level of spoken English are necessary.
Functions to be performed/Workplan: The selected candidate will combine classical genetic approaches with advanced imaging technologies to identify the role of novel topology regulators during mitosis and their molecular mechanisms that may be in the basis of human pathologies associated with chromosome mis-segregation.
Further details on can be found on the following link:
FCT 2022.01782.PTDC TopoChromo Announcement
Deadline: The period for submitting the applications to this Tender, is between 01/06/2023 and 30/06/2023.
For informal enquires, please contact Raquel Oliveira (rcoliveira@igc.gulbenkian.pt)
The double helical structure of DNA imposes a major challenge to all processes involving this molecule: access to its sequence. This requires DNA unwinding, which creates massive changes in the topology of DNA, inducing helical torsion, supercoiling and ultimately sister chromatid intertwining. These topological changes are problematic and need to be resolved to ensure genome stability. This proposal aims to uncover novel topology regulators that operate during mitosis, in order to achieve timely and efficient genome partition at every cell division.
Do you want to join the team?
Eligibility / Requirements: We are seeking a highly motivated and ambitious candidate with a PhD in biological sciences or related areas. Solid expertise in Drosophila genetics and development, chromosome biology and/or live imaging techniques, although not essential, will be considered an advantage. We expect the candidate to drive his/her project with a high degree of independence but within the open-minded collaborative atmosphere of the lab. Good communication skills, including a good level of spoken English are necessary.
Functions to be performed/Workplan: The selected candidate will combine classical genetic approaches with advanced imaging technologies to identify the role of novel topology regulators during mitosis and their molecular mechanisms that may be in the basis of human pathologies associated with chromosome mis-segregation.
Further details on can be found on the following link:
FCT 2022.01782.PTDC TopoChromo Announcement
Deadline: The period for submitting the applications to this Tender, is between 01/06/2023 and 30/06/2023.
For informal enquires, please contact Raquel Oliveira (rcoliveira@igc.gulbenkian.pt)
