See also CHR IN THE NEWS
​​2023
  • Carmo, C.*; Coelho, J.*; Silva, R.D.; Tavares, A.; Boavida, A.; Gaetani, P.; Guilgur, L.G.; Martinho, R.G.; Oliveira, R.A. (2023) A dual-function SNF2 protein drives chromatid resolution and nascent transcripts removal in mitosis EMBO Reports  e56463 Preprint: (2022) BioRxiv ​https://www.biorxiv.org/content/10.1101/2022.11.21.517340v1.full   ​*co-authors 
  • Araujo, M.; Tavares, A.; Vieira, D.V.; Telley, I.A.* and Oliveira, R. A.* (2023) ​​Endoplasmic Reticulum membranes are continuously required to maintain mitotic spindle size and forces Life Science Alliance Jan 2023, 6 (1) e202201540; DOI:10.26508/lsa.202201540 Preprint: (2022) BioRxiv ​https://doi.org/10.1101/2022.05.14.491942   ​*co-corresponding authors 
  • Milagre, I.; Pereira, C.; Oliveira, R.A. (2023) Compromised Mitotic Fidelity in Human Pluripotent Stem Cells. Int. J. Mol. Sci. 2023, 24, 11933. https://doi.org/10.3390/ijms241511933
  • Bowman, J.D*; Silva, N.*; Schüftan, E.; Almeida, J.M; Brattig-Correia, R.; Oliveira, R.A.; Tüttelmann, F.; Enard, D.; Navarro-Costa, P#.; Lynch, V. J.# (2023) Pervasive relaxed selection on spermatogenesis genes coincident with the evolution of polygyny in gorillas Preprint on BioRxiv ​https://www.biorxiv.org/content/10.1101/2023.10.27.564379v2  *, # equal contribution 
Photo by Laura Seaman on Unsplash  
2022
  • Carvalhal, S.; Bader, I.; Rooimans, M.A.; Oostra, A.B.; Balk, J.A.; Feichtinger, R.J.; Beichler, C.; Speicher, M.R.; van Hagen, J.M.; Waisfisz, Q.; van Haelst, M.; Bruijn, M.;  Tavares, A.;  Mayr, J.A.; Wolthuis, R.M.F.; Oliveira, R. A. * and de Lange, J. * (2022) Biallelic BUB1 mutations cause microcephaly, developmental delay, and variable effects on cohesion and chromosome segregation. Science Advances 8, 10.1126/sciadv.abk0114 * co-corresponding authors
  • Soares, M.A.F.; Oliveira, R. A.* and Castro, D.S.*  (2022) Function and regulation of transcription factors during mitosis-to-G1 transition Open Biology  Vol 12, n6 10.1098/rsob.220062 *co-corresponding authors 
  • Horta, C.; Tavares, A.; and Oliveira, R. A.* (2022) ​​Condensin II is required for efficient Spindle Assembly Checkpoint activation in Drosophila male meiosis  BioRxiv ​
2021
  • Soares, M.A.F.; Soares, D.S., Teixeira, V.; Heskol, A.; Bressan, R.B;, Pollard, S.M.; Oliveira, R. A. and Castro, D.S. (2021) Hierarchical reactivation of transcription during mitosis-to-G1 transition by Brn2 and Ascl1 in neural stem cells. Genes & Development 35: 1020-1034
2020
  • Milagre, I.; Pereira, C.; Oliveira, R.A. and Jansen, L.E.T. (2020) Reprogramming of human cells to pluripotency induces CENP-A chromatin depletion. Open Biology  10 200227 http://doi.org/10.1098/rsob.200227

recommended by Faculty Opinions
2019
  • Mirkovic, M.; Guilgur, L.G.; Tavares, A.; Passagem-Santos D and Oliveira, R.A. (2019) Induced aneuploidy in neural stem cells triggers a delayed stress response and impairs adult life span in flies. PLOS Biology 17(2): e3000016. https://doi.org/10.1371/journal.pbio.3000016
  • Carmo C., Araújo M., Oliveira R.A. (2019) Microinjection Techniques in Fly Embryos to Study the Function and Dynamics of SMC Complexes. In: Badrinarayanan A. (eds) SMC Complexes. Methods in Molecular Biology, vol 2004. Humana, New York, NY. https://doi.org/10.1007/978-1-4939-9520-2_19
2018
  • ​Silva, R.D.*, Mirkovic, M.*, Guilgur, L.G., Rathore, O.S., Martinho, R.G., and Oliveira, R.A. (2018). Absence of the Spindle Assembly Checkpoint Restores Mitotic Fidelity upon Loss of Sister Chromatid Cohesion. Current Biology 28, 2837-2844 e2833. 
  • Carvalhal, S.; Tavares A.; Santos M.B.; Mirkovic, M. and Oliveira, R.A. A quantitative analysis of cohesin decay in mitotic fidelity The Journal of Cell Biology Jul 2018 217, 3343-3353. DOI: 10.1083/jcb.201801111
2017
  • Mirkovic, M., and Oliveira, R.A. Centromeric Cohesin: Molecular Glue and Much More. 2017. Prog Mol Subcell Biol. 56:485-513. 
   
  •    Piskadlo, E. , Tavares, A. and Oliveira, R.A. Metaphase chromosome structure is dynamically maintained by Condensin I-directed DNA (de)catenation. eLife 2017;10.7554/eLife.26120
2016
  • Piskadlo, E. and Oliveira, R.A. Novel insights into mitotic chromosome condensation [version 1; referees: 2 approved]. F1000Research 2016, 5(F1000 Faculty Rev):1807 (doi: 10.12688/f1000research.8727.1)
2015
  • Mirkovic, M.; Hutter, L.H.; Novak, B.; Oliveira, R.A. Premature Sister Chromatid Separation
    is poorly detected by the Spindle Assembly Checkpoint as a result of system-level feedback. Cell Reports 13, 1–10 October 20, 2015. (press release)
 
2014
  • Oliveira, R.A.; Kotadia, S; Tavares, A.; Mirkovic, M.; Bowlin, K.; Eichinger, C.S.; Nasmyth, K; Sullivan, W. Centromere-independent accumulation of cohesin at ectopic heterochromatin sites induces chromosome stretching during anaphase. Plos Biology 2014 Oct 07 DOI: 10.1371/journal.pbio.1001962 (press release) 

Pre-chromosome dynamics lab

2013
  • Oliveira, R.A.; and Nasmyth, K; Cohesin cleavage is insufficient for centriole disengagement Current Biology 2013 Jul 22;23(14):R601-3
 
  • Zhang, T.; Oliveira, R.A.; Schmierer, B; Novak, B; Dynamical Scenarios for Chromosome Bi-orientation Biophysical Journal 2013 Jun 18;104(12):2595-606.
 
  • Eichinger, C.S., Kurze, A., Oliveira, R.A., Nasmyth, K., Disengaging the Smc3/kleisin interface releases cohesin from Drosophila chromosomes during interphase and mitosis, EMBO Journal 32, 656-665.


2011
  • He, E.; Kapuy, O.; Oliveira, R.A.; Uhlmann, F; Novák, B. Systems level feedbacks make anaphase switch irreversible ​Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):10016-21.
2010
  • Oliveira, R.A.; Hamilton, R.; Pauli, A.; Davis, I. and Nasmyth, K. Cleavage of cohesin and Cdk inhibition trigger formation of daughter nuclei; Nature Cell Biology 2010 Feb; 12: 185 - 19 
[Selected as a MUST READ paper by Faculty of 1000 Biology; In the top7 in biochemistry selected by The Scientist; featured on the Biochemistry Department news]

  • Nasmyth, K. and Oliveira, R.A. Splitting the nucleus: what’s wrong with the tripartite ring model? Cold Spring Harb Symp Quant Biol. 2010;75:375-88. Epub 2011 Jan 5.
   
  • Pauli, A.; van Bemmel, J.; Oliveira, R.A.; Itoh, T.; Shirahige, K.; van Steensel, B. and Nasmyth, K. A direct role for cohesin in genome-wide gene expression and Ecdysone-response in Drosophila salivary glands. Current Biology. 2010 Oct 26;20(20):1787-98.
 
  • Hamilton, R.S.; Parton, R. M.; Oliveira, R. A.; Ball, G.; Vendra, G.; Nasmyth, K.; Davis, I. ParticleStats: open source software for the analysis of intracellular particle motility. Nucleic Acid Research 2010, Jul 1;38 Suppl:W641-6.
2008
  • Pauli A., Althoff F.*, Oliveira R.A.*, Heidmann S., Schuldiner O., Lehner C.F., Dickson B.J., Nasmyth K. Cell-Type-Specific TEV Protease Cleavage Reveals Cohesin Functions in Drosophila Neurons. ​Developmental Cell. 2008 Feb; 14(2):239-51. (*these authors contributed equally to the work)
2007
  • Oliveira, R.A.; Heidmann, S. and Sunkel, C.E. (2007) Condensin I binds chromatin early in prophase and displays a highly dynamic association with Drosophila mitotic chromosomes. Chromosoma 2007 Jun;116(3):259-74.
2005
  • Oliveira, R. A.; Coelho, P.A. and Sunkel, C.E. (2005) The condensin I subunit Barren/CAP-H is essential for the structural integrity of centromeric heterochromatin during mitosis. Molecular and Cellular Biology. 2005 Oct; 25(20):8971-84.