OPEN CALLS
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RESEARCH TECHNICIAN POSITIONS
INTERNATIONAL TENDER PROCEDURES FOR HIRING A RESEARCH TECHNICIANS WITHIN THE FRAMEWORK OF THE PROJECT “ERC-2020-COG-ChromoSilence-101002391 |
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Have you ever wondered... what is the purpose of transcriptional shutdown upon mitotic entry in higher eukaryotes?
Mitotic Transcriptional Inactivation (MTI) is commonly seen as a simple by-product of the chromosome rearrangements that occur on chromatin upon mitotic entry, serving no other purpose to the cell. Our recently awarded ERC project -ChromoSilence - aims to challenge this dogma and build on the hypothesis that MTI is a vital mechanism to ensure proper nuclear division and maintenance of transcriptional programs, with direct consequences on cell physiology, tissue homeostasis and, ultimately, organism development.
Do you want to join the team?
We have three open positions in this exciting project:
Position Fly: We seek a fly research technician that will assist the work with Drosophila melanogaster (the main model system of the research plan). The project includes the production and maintenance of genetically modified flies, in addition to the ones already available in the lab and the establishment of novel acute inactivation tools. The selected candidate will have as main tasks: a) fly stocks maintenance, b) DNA cloning for fly transformation, c) embryos microinjection. Prior expertise with the use of Drosophila as a model system and/or in basic molecular biology techniques will be considered a valuable asset. Further details on the call and application procedure can be found here: https://euraxess.ec.europa.eu/jobs/165124
Position 1: We seek a research technician to study how perturbations on Mitotic transcriptional Inactivation impact the transcriptional output and consequently embryonic development. The successful candidate will have as main tasks: a) analysis of transcriptional outputs at nascent transcripts using genome-wide approaches, b) analysis of cellular and developmental consequences upon inactivation of specific candidate genes. Prior expertise with Drosophila development and/or genome wide analysis of transcriptional profile will be considered a valuable asset. Further details on the call and application procedure can be found here: https://euraxess.ec.europa.eu/jobs/165122
Position 2: We seek a research technician to study the regulation of critical players in Mitotic Transcription inactivation, using proteomic approaches. Specific tasks include a) proteomic analysis of interactors of known players involved in MTI b) identification and characterisation of novel proteins involved in MTI regulation. Prior expertise with proteomic analysis will be considered a valuable asset. Further details on the call and application procedure can be found here: https://euraxess.ec.europa.eu/jobs/165123
Eligibility / Requirements:
We seek highly motivated candidates with a Master degree in biological sciences or related areas, that are team players, within the collaborative environment of the lab. Prior expertise in some techniques related with the specific tasks, although not essential, will be considered an advantage. Good communication skills and a good level of spoken English are mandatory.
For informal enquires, please contact Raquel Oliveira ([email protected])
Mitotic Transcriptional Inactivation (MTI) is commonly seen as a simple by-product of the chromosome rearrangements that occur on chromatin upon mitotic entry, serving no other purpose to the cell. Our recently awarded ERC project -ChromoSilence - aims to challenge this dogma and build on the hypothesis that MTI is a vital mechanism to ensure proper nuclear division and maintenance of transcriptional programs, with direct consequences on cell physiology, tissue homeostasis and, ultimately, organism development.
Do you want to join the team?
We have three open positions in this exciting project:
Position Fly: We seek a fly research technician that will assist the work with Drosophila melanogaster (the main model system of the research plan). The project includes the production and maintenance of genetically modified flies, in addition to the ones already available in the lab and the establishment of novel acute inactivation tools. The selected candidate will have as main tasks: a) fly stocks maintenance, b) DNA cloning for fly transformation, c) embryos microinjection. Prior expertise with the use of Drosophila as a model system and/or in basic molecular biology techniques will be considered a valuable asset. Further details on the call and application procedure can be found here: https://euraxess.ec.europa.eu/jobs/165124
Position 1: We seek a research technician to study how perturbations on Mitotic transcriptional Inactivation impact the transcriptional output and consequently embryonic development. The successful candidate will have as main tasks: a) analysis of transcriptional outputs at nascent transcripts using genome-wide approaches, b) analysis of cellular and developmental consequences upon inactivation of specific candidate genes. Prior expertise with Drosophila development and/or genome wide analysis of transcriptional profile will be considered a valuable asset. Further details on the call and application procedure can be found here: https://euraxess.ec.europa.eu/jobs/165122
Position 2: We seek a research technician to study the regulation of critical players in Mitotic Transcription inactivation, using proteomic approaches. Specific tasks include a) proteomic analysis of interactors of known players involved in MTI b) identification and characterisation of novel proteins involved in MTI regulation. Prior expertise with proteomic analysis will be considered a valuable asset. Further details on the call and application procedure can be found here: https://euraxess.ec.europa.eu/jobs/165123
Eligibility / Requirements:
We seek highly motivated candidates with a Master degree in biological sciences or related areas, that are team players, within the collaborative environment of the lab. Prior expertise in some techniques related with the specific tasks, although not essential, will be considered an advantage. Good communication skills and a good level of spoken English are mandatory.
For informal enquires, please contact Raquel Oliveira ([email protected])
