OPEN CALLS
POSTDOCTORAL POSITION
INTERNATIONAL TENDER PROCEDURE FOR HIRING A POSTDOCTORAL RESEARCHER WITHIN THE FRAMEWORK OF THE PROJECT “ERC-2020-COG-ChromoSilence-101002391
INTERNATIONAL TENDER PROCEDURE FOR HIRING A POSTDOCTORAL RESEARCHER WITHIN THE FRAMEWORK OF THE PROJECT “ERC-2020-COG-ChromoSilence-101002391
Have you ever wondered... what is the purpose of transcriptional shutdown upon mitotic entry in higher eukaryotes?
Mitotic Transcriptional Inactivation (MTI) is commonly seen as a simple by-product of the chromosome rearrangements that occur on chromatin upon mitotic entry, serving no other purpose to the cell. Our recently awarded ERC project -ChromoSilence - aims to challenge this dogma and build on the hypothesis that MTI is a vital mechanism to ensure proper nuclear division and maintenance of transcriptional programs, with direct consequences on cell physiology, tissue homeostasis and, ultimately, organism development.
Do you want to join the team?
Eligibility / Requirements: We are seeking a highly motivated and ambitious candidate with a PhD in biological sciences or related areas. Solid expertise in Drosophila development /human cell culture and/or genome-wide transcriptional analysis, although not essential, will be considered an advantage. We expect the candidate to drive his/her project with a high degree of independence but within the open-minded collaborative atmosphere of the lab. Good communication skills, including a good level of spoken English are necessary.
Functions to be performed/Workplan: The selected candidate will join the Chromosome Dynamics Laboratory in March 2023 (flexible). Research in the lab aims at understanding how chromosomes are assembled and how their morphology influences the fidelity of cell division. Successful candidates will join an ERC-funded team (ERC-2020-COG-ChromoSilence- 101002391). The successful candidate will focus on studying the consequences of failures in mitotic transcription inactivation (MTI). Specific tasks include: 1) analysis of transcriptional outputs using genome-wide approaches to monitor ongoing transcription; 2) analysis of developmental consequences upon failures of specific candidates.
Further details on can be found on the following link:
ERC-2020-COG-ChromoSilence-101002391 Call Announcement
Deadline: The period for submitting the applications to this Tender, is between 04/01/2023 and 15/02/2023.
For informal enquires, please contact Raquel Oliveira (rcoliveira@igc.gulbenkian.pt)
Mitotic Transcriptional Inactivation (MTI) is commonly seen as a simple by-product of the chromosome rearrangements that occur on chromatin upon mitotic entry, serving no other purpose to the cell. Our recently awarded ERC project -ChromoSilence - aims to challenge this dogma and build on the hypothesis that MTI is a vital mechanism to ensure proper nuclear division and maintenance of transcriptional programs, with direct consequences on cell physiology, tissue homeostasis and, ultimately, organism development.
Do you want to join the team?
Eligibility / Requirements: We are seeking a highly motivated and ambitious candidate with a PhD in biological sciences or related areas. Solid expertise in Drosophila development /human cell culture and/or genome-wide transcriptional analysis, although not essential, will be considered an advantage. We expect the candidate to drive his/her project with a high degree of independence but within the open-minded collaborative atmosphere of the lab. Good communication skills, including a good level of spoken English are necessary.
Functions to be performed/Workplan: The selected candidate will join the Chromosome Dynamics Laboratory in March 2023 (flexible). Research in the lab aims at understanding how chromosomes are assembled and how their morphology influences the fidelity of cell division. Successful candidates will join an ERC-funded team (ERC-2020-COG-ChromoSilence- 101002391). The successful candidate will focus on studying the consequences of failures in mitotic transcription inactivation (MTI). Specific tasks include: 1) analysis of transcriptional outputs using genome-wide approaches to monitor ongoing transcription; 2) analysis of developmental consequences upon failures of specific candidates.
Further details on can be found on the following link:
ERC-2020-COG-ChromoSilence-101002391 Call Announcement
Deadline: The period for submitting the applications to this Tender, is between 04/01/2023 and 15/02/2023.
For informal enquires, please contact Raquel Oliveira (rcoliveira@igc.gulbenkian.pt)
